In Oracle RAC environments, Oracle recommends that you let the Oracle Agent manage Oracle listeners for Oracle Databases.

• Local Listener for an Oracle RAC Database
  The local listener, or default listener, is located in the Grid home when you have Oracle Grid Infrastructure installed. The listener.ora file is located in the Grid_home/network/admin directory.
• Remote Listeners for an Oracle RAC Database
  A remote listener is a listener residing on one computer that redirects connections to a database instance on another computer. For example, SCAN listeners are remote listeners.
• Managing Multiple Listeners for an Oracle RAC Database
  Review to understand how to use SRVCTL and TNS_ADMIN to manage listeners
• How Oracle Database Uses the Listener File (listener.ora)
  The listener.ora file is the configuration file for a listener. It can include the protocol addresses it is accepting connection requests on, a list of the database and other services it is listening for, and control parameters used by the listener.